All in all, ASUS Update is a life-saving tool when you need to address some hardware issues by updating the BIOS, so give it a shot if you really have to.
It comes with a freeware license, but don’t mess around with it unless you really know what you’re doing.
If you are on a personal connection, like at home, you can run an anti-virus scan on your device to make sure it is not infected with malware.
If you are at an office or shared network, you can ask the network administrator to run a scan across the network looking for misconfigured or infected devices.
If you have an Rampage III extreme, rename the file to R3E.